Publications
Designing Peptides on a Quantum Computer
Mulligan VK, Melo H, Merritt HI, Slocum S, Weitzner BD, Watkins AM, Renfrew PD, Pelissier C, Arora PS, Bonneau R
De novo design of bioactive protein switches
Langan RA, Boyken SE, Ng AH, Samson JA, Dods G, Westbrook AM, Nguyen TH, Lajoie MJ, Chen Z, Berger S, Mulligan VK, Dueber JE, Novak WRP, El-Samad H, Baker D
Transesterification of a Tertiary Alcohol by Engineered Candida Antarctica Lipase
Lofgren J, Gorbe T, Oschmann M, Humble MS, Backvall JE
Enantioselective Aminohydroxylation of Styrenyl Olefins Catalyzed by an Engineered Hemoprotein
Cho I, Prier CK, Jia ZJ, Zhang RK, Gorbe T, Arnold FH
Programmable design of orthogonal protein heterodimers
Chen Z, Boyken SE, Jia M, Busch F, Flores-Solis D, Bick MJ, Lu P, VanAernum ZL, Sahasrabuddhe A, Langan RA, Bermeo S, Brunette TJ, Mulligan VK, Carter LP, DiMaio F, Sgourakis NG, Wysocki VH, Baker D
Accurate computational design of multipass transmembrane proteins
Lu P, Min D, DiMaio F, Wei KY, Vahey MD, Boyken SE, Chen Z, Fallas JA, Ueda G, Sheffler W, Mulligan VK, Xu W, Bowie JU, Baker D
Comprehensive computational design of ordered peptide macrocycles
Hosseinzadeh P, Bhardwaj G, Mulligan VK, Shortridge MD, Craven TW, Pardo-Avila F, Rettie ST, Kim D, Silva DA, Ibrahim YM, Webb IK, Cort JR, Adkins JN, Varani G, Baker D
Improved Enantioselectivity of Subtilisin Carlsberg towards Secondary Alcohols by Protein Engineering
Dorau R, Gorbe T, Humble MS
Accurate de novo design of hyperstable constrained peptides
Bhardwaj G, Mulligan VK, Bahl CD, Gilmore JM, Harvey PJ, Cheneval O, Buchko GW, Pulavarti SV, Kaas Q, Eletsky A, Huang PS, Johnsen WA, Greisen PJ, Rocklin GJ, Song Y, Linsky TW, Watkins A, Rettie SA, Xu X, Carter LP, Bonneau R, Olson JM, Coutsias E, Correnti CE, Szyperski T, Craik DJ, Baker D