Publications

Designing Peptides on a Quantum Computer

bioRxiv, 2 Sep 2019

Mulligan VK, Melo H, Merritt HI, Slocum S, Weitzner BD, Watkins AM, Renfrew PD, Pelissier C, Arora PS, Bonneau R

De novo design of bioactive protein switches

Nature, 24 Jul 2019

Langan RA, Boyken SE, Ng AH, Samson JA, Dods G, Westbrook AM, Nguyen TH, Lajoie MJ, Chen Z, Berger S, Mulligan VK, Dueber JE, Novak WRP, El-Samad H, Baker D

Transesterification of a Tertiary Alcohol by Engineered Candida Antarctica Lipase

ChemBioChem, 24 Jan 2019

Lofgren J, Gorbe T, Oschmann M, Humble MS, Backvall JE

Enantioselective Aminohydroxylation of Styrenyl Olefins Catalyzed by an Engineered Hemoprotein

Angewandte Chemie, 2 Jan 2019

Cho I, Prier CK, Jia ZJ, Zhang RK, Gorbe T, Arnold FH

Programmable design of orthogonal protein heterodimers

Nature, 19 Dec 2018

Chen Z, Boyken SE, Jia M, Busch F, Flores-Solis D, Bick MJ, Lu P, VanAernum ZL, Sahasrabuddhe A, Langan RA, Bermeo S, Brunette TJ, Mulligan VK, Carter LP, DiMaio F, Sgourakis NG, Wysocki VH, Baker D

Accurate computational design of multipass transmembrane proteins

Science, 2 Mar 2018

Lu P, Min D, DiMaio F, Wei KY, Vahey MD, Boyken SE, Chen Z, Fallas JA, Ueda G, Sheffler W, Mulligan VK, Xu W, Bowie JU, Baker D

Comprehensive computational design of ordered peptide macrocycles

Science, 15 Dec 2017

Hosseinzadeh P, Bhardwaj G, Mulligan VK, Shortridge MD, Craven TW, Pardo-Avila F, Rettie ST, Kim D, Silva DA, Ibrahim YM, Webb IK, Cort JR, Adkins JN, Varani G, Baker D

Accurate de novo design of hyperstable constrained peptides

Nature, 14 Sep 2016

Bhardwaj G, Mulligan VK, Bahl CD, Gilmore JM, Harvey PJ, Cheneval O, Buchko GW, Pulavarti SV, Kaas Q, Eletsky A, Huang PS, Johnsen WA, Greisen PJ, Rocklin GJ, Song Y, Linsky TW, Watkins A, Rettie SA, Xu X, Carter LP, Bonneau R, Olson JM, Coutsias E, Correnti CE, Szyperski T, Craik DJ, Baker D